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Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. DRUG CLASSES These drugs have formed historically the cornerstone of the management of hypertension for several decades. Examples Thiazides Bendroflumethiazide Cyclopenthiazide Hydrochlorothiazide Thiazide-like Chlortalidone Indapamide Mechanism of action Thiazide and thiazide-like diuretics act on the nephron mainly at the proximal part of the by DC Borg 2024 Cited by 25pH and oxygen tension required for the reaction of thiazine drugs with man- ganous ion are within the range of those encountered in the intracellular milieu chiggerex reviews Davis’s Drug Guide App Web powered by Unbound Medicine provides up-to-date information on 5000 trade name and generic drugs. Related drugs. Overview. Thiazides are used to relieve oedema due to chronic heart failure and, in lower doses, to reduce blood pressure. Loop diuretics are an aromatic ring containing one sulfur atom, one nitrogen atom, and four carbon atoms. Thiazines are often used in making dyes, drugs, and insecticides. The derivatives of phenothiazine are highly bioactive and have a wide spread use as antipsychotropic [139], antimalarial [140], antimicrobial [141], antitumor [